The fourth annual Knoxville Horror Film Fest ran October 25-27, 2012 at Relix Variety Theatre and, for the first time, an evening screening at Regal Cinemas Downtown West 8.

Special events included the second annual Grindhouse Grind-out.

Missing from Letterboxd: Why So Serial?, The Find, Mad Dog, Il Trillo Del Diavolo, Harvest Road, Dummy, Black Midas, Hell's Belles, eSnuff Said, Zydrome, Killing Me Softly, A Service Worth Providing, Blindspot and Soulmates.