Well... that was really something. I finally found a Coen Brothers film I didn't like. It's not that The Ladykillers is a terribly bad film, it's just not good and doesn't showcase what makes the Coens so good.
There are a number of actors I like, some even do a pretty good job (Hanks, Simmons). Then there's Wayans, and I'm not even sure I would put it all on him, it seemed like he was a caricature of what white people think black people are like. It was uncomfortable to watch.
Everything is all over the place too. A lot of the time the Coens have that dynamic and are able to balance it and make it work to the greater good of the story, not this time though. Suddenly we're following this storyline, then that storyline, then we're at the climax, then there's another 40 minutes. It's rough. I'm not sure I'll ever watch this one again.